PICC与CVC置管在肝细胞癌患者中的应用比较

Application of PICC and CVC on patients with hepatocellular carcinoma

目的比较经外周穿刺中心静脉置管(PICC)与锁骨下静脉置管(CVC)在肝细胞癌患者治疗中的应用效果。方法 90例确诊为肝细胞癌的患者,随机选择留置PICC和CVC导管,PICC组、CVC组各45例,观察并比较一次性穿刺成功率、导管留置时间、并发症发生率等。结果 PICC组一次性置管成功率为91.1%,明显高于CVC组的75.6%(χ2=3.92,P=0.041);两组留置时间中位数比较,PICC组为182天,明显长于CVC组的65天(u=3.11,P=0.023);并发症总发生率比较,PICC组为8.8%,明显低于CVC组的24.4%(χ2=3.92,P=0.041)。结论 PICC较CVC方法 ,一次性穿刺成功率高、导管留置时间长、并发症少,应成为需要长期置管治疗的肝细胞癌患者的首选。

Objective To compare the therapeutic effect of central venous catheter （PICC） and central venous catheter （CVC） on patients with liver cancer. Methods Total of 90 patients with hepatocellular carcinoma were randomly divided into PICC group and CVC group, 45 cases in each group. The success rate of onetime puncture, catheterization time and complications were observed. Results The success rate of one-time puncture in PICC group （91.1%） was significantly higher than that of the CVC group （75.6%） （χ2 = 3.92, P = 0.041）; the catheterization time of PICC group （182 days） was significantly longer than that of the CVC group （65 days） （u = 3.11, P = 0.023）; the incidence of complications in PICC group （8.8%） was lower than that of the CVC group （24.4%） and the difference were statistically significant （χ2 = 3.92, P = 0.041）. Conclusions The PICC should be the first choice for liver cancer patients who need long-term catheterization treatment.