三乙醇胺乳膏保留灌肠治疗恶性肿瘤放化疗后放射性直肠炎临床观察

Triethanolamine cream retention enema in malignant tumor radiation and chemotherapy after concurrent radiation proctopathy in application effect

目的探讨三乙醇胺乳膏保留灌肠在恶性肿瘤放化疗后并发放射性直肠炎中的应用效果。方法选择昆明医科大学第一附属医院2011-01—2014-12收治的50例放射性直肠炎患者为研究对象。随机分为对照组与观察组各25例，其中对照组患者给予维生素B12、地基米松、温开水进行保留灌肠；观察组以此为基础，再给予三乙醇胺乳膏，对比两组患者的治疗效果。结果观察组患者的治疗总有效率96％，对照组76％，两组比较差异有统计学意义，P〈0．05。结论放射性直肠炎使用三乙醇胺乳膏保留灌肠治疗，能够提高患者的临床疗效，改善患者的肠道环境，降低患者远期不良反应的发生率。

OBJECTIVE To explore triethanolamine cream retention enema in the application of radiation proctopa- thy effect. METHODS Randomly selected between January 2011 and December 2014 to 50 patients with radiation proc- topathy in our hospital, were divided into control group and observation group, control group patients give vitamin B12, dexamethasone, water retention enema, the observation group on this basis, to give triethanolamine cream, compare the treatment effect of two groups of patients. RESULTS Observation group the treatment of patients with total effective rate was 96%, control group is 76%, the difference significant （P〈0. 05）. CONCLUSION The use of radiation proc- topathy triethanolamine cream retention enema treatment, improve the patient＇s clinical curative effect, improve the intes- tinal environment of patients, reduce the incidence of patients with long-term adverse reactions.