特异性转移因子对卵巢癌患者淋巴细胞转化和白细胞粘附抑制试验的影响

Effect of Specific Transfer Factor on Lymphocyte Transformation Rate and Leukocyted Adherence Inhibition Rate of Ovary Carcinoma Patients

目的 观察特异性转移因子在化疗的卵巢癌患者的体内生物学活性。方法 对化疗的卵巢癌患者用特异性转移因子免疫治疗。利用淋巴细胞转化试验及白细胞粘附抑制试验检测外周血淋巴细胞、白细胞。结果 实验组淋巴细胞转化率 ,有 3 4 4%显著高于对照组 (P <0 0 1)。实验组白细胞粘附抑制试验显著高于对照组 (P <0 0 5 )。结论 山羊来源的特异性转移因子对化疗卵巢癌患者 ,有促进淋巴细胞转化率及白细胞粘附抑制率作用。

Objective To observe the activity of specific transfer factor (STF) in patients with ovary carcinoma on chemotherapy in vivo.Methods The chemotherapy and immunotherapy with STF were used in patients with ovary carcinoma.The lymphocyte transformation assay (LT) and leukocytes adherence inhibition assay (LAI) were used to test lymphocytes and leukocytes of patients with ovary carcinoma.Results The LT rate of 34.1% in experimental group was significantly higher than that of control group ( P <0 01).The LAI rate of experimental group was significantly higher than that of control group ( P <0 05).Conclusion STF obtained from goat promoted the LT rate and LAI rate of patients with ovary carcinoma on chemotherapy after operation in vivo.