回阳饮治疗慢性肺心病急性加重期临床观察

Clinical Observation of Hui Yang Yin on Acute Exacerbation of Chronic Cor Pulmonale

目的：观察在西医常规治疗上采用自拟方回阳饮对慢性肺心病急性加重期的临床疗效。方法：将40例心病科住院患者设定为对照组,予常规治疗,40例肺病科住院患者设定为治疗组,予常规治疗加用自拟回阳饮;比较两组临床总疗效及各项指标的变化。结果：治疗组总有效率为97.50%（95%CI=86.72%-99.90%）,单纯西医常规治疗为77.50%（95%CI=64.56%-90.44%）,两组综合疗效比较（u=4.0465,P〈0.0001）,差异有显著性意义;且可有效改善喘息气短、恶心纳差、咳嗽咳痰中医证候积分,改善实验检查参数（P〈0.05）。结论：治疗组临床疗效优于对照组的证据明显,其收益为OR=0.11（95%CI=0.01-0.92）,NNT=5（95%CI=2.90-18.15）。

Objective ： To observe the clinical effects of treating the acute exacerbation of chronic cor pulmonale with Hui Yang Yin on the basis of conventional western medicine therapy. Methods：40 inpatients of heart depart- ment were set as the control group and given the conventional treatnemt. 40 inpatients of pulmonary department were set as the treatment group, and given the conventional treatnemt plus Hui Yang Yin. The overall clinical effects and the changes of every index were compared in two groups. Results： The total effective rate of treatment group was 97.50% （95% CI = 86.72% -99.90% ）,while the control group （alone with conventional western medicine treatment） 77.50% （95% CI = 64.56% -90.44% ）. The comprehensive effects of two groups were compared （ u = 4. 046 5, P 〈 0. 000 1 ）, the difference was statistically significant. The treatment group could improve effectively wheezing and shortness of breath, nausea and anorexia, cough and sputum etc. TCM syndrome scores, .as well as experimental examination parameters （ P 〈 0.05 ）. Conclusion ： It has the sufficient evidences that the clinical effect of treatment group is superior to that of control group. Its benefits is OR =0. 11 （95% CI =0. 01 0.92）, NNT =5 （95% CI =2.90 - 18.15）.