摘要
以冰醋酸为溶剂,以邻香兰素、液溴、溴化钾为原料溴化合成5-溴邻香兰素。采用正交试验法对影响收率因素进行考察。最佳条件为:反应温度为100°C,滴加液溴时间为50min,反应时间为90min。在此条件下,产品的产率为92.5%。
5- bromo- o- vanillin was synthesizedby using o- vanillin,liquid bromine,potassium bromide as raw material,cetic acid as solvent. Factors influencing the yield were investigated by the orthogonal experimental method. The optimum conditions were： reaction temperature is 100℃,dropping the,liquid bromine during the time of 50 min,the reaction time is 90 min. Under the optimum condition,the yield of the product was 92. 5%.
出处
《山东化工》
CAS
2015年第21期42-42,50,共2页
Shandong Chemical Industry
