通心络胶囊对脑梗死恢复期患者血液流变学及血脂水平的影响

The Influence of Tongxinluo Capsule on Blood Rheology and Blood Lipid of Patients with Cerebral Infarction in Recovery Stage

目的:观察通心络胶囊对脑梗死恢复期患者血液流变学及血脂水平的影响。方法:将93例脑梗死恢复期患者随机分为观察组47例和对照组46例,对照组患者服用肠溶阿司匹林和盐酸氟桂利嗪胶囊治疗,观察组患者在此基础上给予通心络胶囊治疗,疗程均为3个月。检测两组患者治疗前后神经功能缺损评分、血液流变学和血脂水平。结果:治疗后两组患者神经功能缺损评分均有明显改善,并且观察组患者神经功能缺损评分低于对照组,差异有统计学意义(P<0.05);治疗后两组患者全血黏度(高切)、全血比黏度(低切)、血浆黏度、TC和TG水平明显降低,而HDL-C水平明显升高,并且观察组患者上述指标水平改善程度优于对照组,差异有统计学意义(P<0.05)。结论:通心络胶囊可有效调节血液流变学和血脂水平,对脑梗死恢复期患者具有较好疗效。

Objective： To observe the influence of Tongxinluo Capsule（TXLC） on blood theology and blond lipid of patients with cerebral infarction in recovery stage. Methods：Ninety-three patients with cerebral infarction in recovery stage were randomly di- vided into the observation group and the control group, with 47 and 46 cases in each group. The ones in the control group were given enteric-coated aspirin and flunarizine hydrochioride capsule, while the ones in the control group were added TXLC on the basic： treatment of the control group. Both groups regarded 3 months as a eourse. Then nerve function impairment score, blood theology anti blood lipid before and after the treatment in both groups were detected. Results： After the treatment, nerve function impairment scores of both groups were obviously improved; The observation group was lower than the control group; And the difference between them had statistical significance （ P 〈 0.05 ）. After the treatment, the whole tdood viscosity （ high cut） , whole blood contrast viscosity （low cut） , plasma viscosity, TC and TG levels before and after the treatment in both groups were significantly decreased, while HDL-e level was significantly increased ; The improved degrees of the above indexes of the observa- tion group were better than those of the control group ; And the differences between them had statistical significance （ P 〈 0.05 ）. Conclusion ： TXLC has better clinical curative effect on patients with cerebral infarction in recovery stage, can effectively regulate blood rheology and blood lipid levels.