头针配合实时认知功能训练对阿尔茨海默病认知功能障碍患者脑血流的影响

Effect of Scalp Acupuncture plus Real-time Cognitive Training on Cerebral Blood Flow in Alzheimer Disease Patients

目的观察头针配合实时认知功能训练对阿尔茨海默病认知功能障碍患者脑血流的影响。方法将100例阿尔茨海默病认知功能障碍患者随机分为治疗组和对照组,每组50例。两组均给予原基础疾病的治疗,治疗组在此基础上采用头针配合实时认知功能训练治疗,对照组采用口服银杏叶提取物药片治疗。治疗3个月后,采用经颅多普勒检测两组患者治疗前后左侧椎动脉(LVA)、右侧椎动脉(RVA)和大脑中动脉(NCA)的平均流速(Vm)。结果治疗组治疗后LVA、RVA及MCA的Vm与同组治疗前比较,差异均具有统计学意义(P<0.01)。治疗组治疗后LVA、RVA及MCA的Vm与对照组比较,差异均具有统计学意义(P<0.05)。结论头针配合实时认知功能训练能改善阿尔茨海默病认知功能障碍患者的脑循环,提高脑血流量。

Objective To investigate the effect of scalp acupuncture plus real-time cognitive training on cerebral blood flow in Alzheimer disease patients with cognitive disorder.Methods One hundred Alzheimer disease patients with cognitive disorder were randomly allocated to treatment and control groups, 50 cases each. Both groups received treatment for the primary disease. In addition, the treatment group received scalp acupuncture plus real-time cognitive training and the control group took Ginkgo leaf extract tablets. Mean flow velocity （Vm） in the left vertebral artery （LVA）, right vertebral artery （RVA） and middle cerebral artery （MCA） were measured using transcranial Doppler in the two groups of patients before and after three months of treatment.Results There were statistically significant pre-/post-treatment differences in LVA, RVA and MCA Vm in the two groups （P〈0.01）. There were statistically significant post-treatment differences in LVA, RVA and MCA Vm between the treatment and control groups （P〈0.05）.Conclusions Scalp acupuncture plus real-time cognitive training can improve cerebral circulation and increase cerebral blood flow in Alzheimer disease patients with cognitive disorder.