1999～2013年西安市首次献血志愿者输血相关感染性指标阳性率的趋势研究

The prevalence and trends of transfusion-transmissible infectious related measures among first-time,voluntary blood donors in Xi′an from 1999 to 2013

目的本研究分析了1999~2013年西安地区首次献血志愿者输血相关感染性指标检测阳性的长期趋势,以评估西安市输血安全态势。方法对1999~2013年西安市西京医院血液中心所有的首次献血者中乙型肝炎病毒（HBV）、丙型肝炎病毒（HCV）、人免疫缺陷病毒（HIV）和梅毒螺旋体（TP）的感染数据进行趋势检验分析。结果 1999~2013年的415 657例首次献血者中,上述病原体的阳性率依次为HBV 1.02%,HCV 0.55%,HIV 0.05%,TP 0.46%。HBV和HCV感染具有下降趋势。结论HBV感染是西安地区血液安全性的主要威胁,而HIV、TP的流行率增加可能也成为一种潜在的威胁。

Objective The increasing prevalence of infectious diseases is threatening the biological safety of donated blood in developing countries.This study was to analyze the prevalence of transfusion-transmissible infectious related measures among firsttime,voluntary blood donors from 1999 to 2013in China.Methods From 1999 to 2013,all first-time donors in the Xi′an Blood Service were screened for hepatitis B virus（HBV）,hepatitis C virus（HCV）,human immunodeficiency virus（HIV）and Treponemiapallidum（TP）and analyzed by trend test analysis.Results The positive rates of HBV,HCV,HIV,and TP in the 415 657 blood donors were 1.02%,0.55%,0.05%,and 0.46%,respectively.The prevalence of HBV and HCV presented a decreased trend.Conclusion HBV infection is the primary threat to the blood safety,while the increasing prevalence of TP and HIV might also be a potential threat.