期刊文献+

宁波某地区育龄期妇女宫颈癌前病变的HPV亚型的流行病学调查 被引量:2

下载PDF
导出
摘要 目的:调查宁波某地区育龄期妇女有宫颈癌前病变的感染23种人乳头瘤病毒(HPV)基因型的分子流行病学特点。方法:520例宫颈癌前病变患者,作病理组织活检明确诊断,应用聚合酶链反应(PCR)技术检测HPV6等23种基因型,分析亚型特点。结果:HPV患者总感染率为100%;其中HPV16,HPV33,HPV52感染率明显高于其他亚型。结论:本研究提供了23种常见HPV基因型的本地区分子流行病学资料,对HPV疫苗开发、应用及宫颈癌的防治具有现实意义。
出处 《中国高等医学教育》 2015年第11期128-128,130,共2页 China Higher Medical Education
基金 2012年镇海区农业和社会发展科技项目(项目编号:2012S1012)
  • 相关文献

参考文献3

二级参考文献18

  • 1BULK S, BERKHOF J, BULKMANS N W, et al. Preferential risk of HPV16 for squamous celt carcinoma and of HPV18 for adenocaicinoma of the cervix compared to women with normal cytology in the Northern- lands[ J]. Br J Cancer,2006,94( 1 ) : 171-175.
  • 2AULT KA, GIULIANO A R, EDWARDS R P, et al. A phase I study to evaluate a human papillomavims(HPV) type 18 L1 VLP vaccine[ J]. Vaccine ,2004,22 ( 23-24 ) :3004-3007.
  • 3ZUR HAUSEN H. Cervical carcinoma and human papillomavims: on the road to preventing a major human cancer [ J ]. J Natl Cancer Inst, 2001,93 (4) :252-253.
  • 4MUNOZ N, BOSCH F X, DE SANJOSE S, et al. Epidemiologic classification of human papillomavirus types associated with cervical cancer [ J]. N Engl J Med ,2003,348(6) :518-527.
  • 5LEE S A,KANG D,SEO S S,et al. Multiple HPV infection in cervical cancer screened by HPV DNAChip [ J ]. Cancer Lett, 2003,198 ( 2 ) : 187-192.
  • 6MUNOZ N,BOSCH F X,CASTELLSAGUE X,et al. Against which human papillomavirus types shall we vaccinate and screen? The international perspective [ J ]. Int J Cancer,2004,111 ( 2 ) :278-285.
  • 7RALSTON HOWE E, LI Z, MCGLENNEN R C, et al. Type-specific prevalence and persistence of human papillomavirus in women in the United States who are referred for typing as a component of cervical cancer screening [ J].Am J Obsted Gynecol, 2009, 200 ( 3 ) : 245 e1- e7.
  • 8PATRICIA C,ANNE R, ALEXIA S, et al. Different outcome of invasive cervical cancer associated with high-risk versus intermediate-risk HPV genotype [ J ]. Int J Cancer,2009,124 (4) :778-782.
  • 9Yuen KY,Woo PC,Teng JL,et a|. Laribacter hongkong gensisgen, nov a novel Gram-negative bacterium isolated from a cirrhotic patient with bacteremia and empyema[J]. J Clin Microbiol, 2001 , 39 ( 12 ) : 4227-4232.
  • 10Woo PC,Lau SK,Teng JL,et al. Association of Laribacter hongkong gensis in community-acquired gastroenterilis with travel and eating fish :amuhit:entre ease-control study[J]. Lancet,2004,36(23) : 1941-1947.

共引文献18

同被引文献29

引证文献2

二级引证文献25

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部