摘要
目的探讨静滴间苯三酚对于体外冲击波碎石(ESWL)后输尿管结石排出效果的影响。方法将200例患者随机分为观察组和对照组各100例,分别给予ESWL前30 min和后30 min静滴间苯三酚的治疗措施,比较两组排石效果和排石时间。结果两组比较,输尿管中段结石的治疗效果未见差异,但在治疗输尿管上、下段结石时,观察组明显优于对照组;排石时间比较,无论结石存在于输尿管任何部位,观察组始终少于对照组,且差异具有统计学意义(p<0.05)。结论 ESWL前30 min静滴间苯三酚,正好符合其药代动力学,使血药浓度在ESWL时达到峰值,尤其治疗输尿管上、下段结石时,疗效最佳。
Objective To observe the impact of intravenous infusion of phloroglucinol on ureteral calculi expulsion after extracorporeal shock wave lithotripsy（ ESWL）. Methods 200 cases of ureteral calculi were randomly divided into the observation group and the control group equally. The observe group was given intravenous infusion of Phloroglucinol over 30 min before ESWL,and the control group over 30 min after ESWL. The two groups were compared in terms of expulsion effects and expulsion time. Results There was no significant difference in the treatment outcome of middle ureteral calculi in the two groups. But the outcomes of upper and lower ureteral calculi were better than those in the control group（ p〈0. 05）. The expulsion time in the observation group was significantly shorter than that in the control group in the 3 sections of ureter（ p〈0. 05）. Conclusion Intravenous infusion of Phloroglucinolover 30 min before ESWL accords with pharmacokinetics making peak plasma concentration attained with ESWL,especially helping achieving optimal efficacy in treatment of upper and lower ureters.
出处
《现代医院》
2015年第1期31-33,共3页
Modern Hospitals
