养阴活血法治疗肾病综合征高凝状态的临床观察

Clinical Treatment of nephrotic syndrome Yin and activating blood hypercoagulable state

目的：探讨养阴活血法治疗肾病综合征高凝状态的临床疗效,评价其安全性。方法：选取2013年4月-2015年4月我院收治的60例肾病综合征高凝状态患者,按治疗方法分为对照组（30例）和观察组（30例）,对照组行西药常规治疗,观察组加用养阴活血法（中药汤剂加味二至丸）治疗,对比两组临床治疗效果及不良反应发生情况。结果：两组患者治疗前的APTT、PT、FIB比较（P〉0.05）,差异无统计学意义;观察组治疗后的APTT、PT均显著高于对照组（P〈0.05）,FIB、不良反应总发生率均显著低于对照组（P〈0.05）,差异有统计学意义。结论：应用养阴活血法治疗肾病综合征高凝状态,疗效确切,安全可靠,利于患者康复,值得临床推广。

Objective To investigate the clinical efficacy of Nourishing Yin Method hypercoagulahle state in nephrotic syndrome treatment, evalu- ate its safety. Methods April 2013 - April 2015 in our hospital 60 cases of patients with nephrotie syndrome hypercoagnlable state, according to the different treatment methods were divided into control group （30 cases） and observation group （30 cases）and control group underwent medicine Conventional treatment, observation group Yin and activating blood method （TCM decoction and two to Pill） treatment on its basis, clinical treatment compared two groups of patients and adverse events. Results AP3~F two groups of patients before treatment, PT, FIB com- parison （P〉0.05）, the difference was not statistically significant; AFTT observation group after treatment, PT were significantly higher（P〈0.05 ）, and FIB, bad The overall incidence rate of response was significantly lower than the control group （P〈0.05）, the difference was statistically sig- nificant. Conclusion Treatment of Nourishing Yin hypercoagulable state in patients with nephrotic syndrome, effective, safe and reliable, which will help the rehabilitation of patients, worthy of promotion.