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腹腔镜与开腹手术对胃癌根治术患者β-ep、TNF-α及IL-6水平的影响 被引量:9

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摘要 研究腹腔镜与开腹手术对胃癌根治术患者血清β内啡肽(β-ep)、肿瘤坏死因子-α(TNF-α)及白细胞介素-6(IL-6)的影响。选择2010年1月—2011年9月接受根治手术的胃癌患者100例,其中观察组及对照组各50例。对照组实施开腹手术,观察组实施腹腔镜手术,术后随访3年,对比两组手术的相关指标,治疗前后β-ep、TNF-α及IL-6水平及两组的近远期生存率。观察组的手术时间、住院时间、肛门排气时间与术中出血量均显著少于对照组,差异均有统计学意义(P<0.05)。两组术前β-ep、TNF-α及IL-6水平差异均无统计学意义(P>0.05)。但观察组术后β-ep、TNF-α及IL-6水平均显著低于对照组,差异均有统计学意义(P<0.05)。两组术后1、3年生存率比较,差异均无统计学意义(P<0.05)。腹腔镜胃癌根治术治能够有效减少患者手术应激反应,降低手术创伤,安全性较高。
出处 《中国现代普通外科进展》 CAS 2015年第10期818-820,共3页 Chinese Journal of Current Advances in General Surgery
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