糖尿病肾病研究进展

Researching Progress of Diabetic Nephropathy

近年来,随着糖尿病患病率的升高,糖尿病肾病也已经成为危害人类健康的危险疾病。糖尿病肾病既是糖尿病的常见并发症之一,也在肾病中占据重要的位置。糖尿病肾病的发病机制非常复杂,因其涉及到的人体生物代谢的分子层面,固对其研究也是比较困难的,至今尚无明确的发病机制。现在多数研究表明,糖尿病肾病的发病机制多与遗传、糖代谢异常、脂代谢异常、微循环障碍、细胞因子作用、炎症作用、激肽释放酶-激肽系统等有关。据研究发现,中医药治疗糖尿病肾病具有明显的疗效。

In recent years,diabetic nephropathy has become a threat to human health with increasing prevalence rate of diabetes.Diabetic nephropathy is one of the common complications of diabetes,also occupies an important position in nephropathy. The pathogenesis of diabetic nephropathy is very complex,as it relates to the molecular level human biological metabolism. Therefore the research on it is more difficult and so far there is no clear pathogenesis. Nowadays,most studies show that the pathogenesis of diabetic nephropathy is related to heredity,abnormal glucose metabolism,abnormal lipid metabolism,microcirculatory disturbance,the role of cytokines,inflammation,kallikrein-kinin system,and so on. According to researches,the treatment of diabetic nephropathy with traditional Chinese medicine has obvious curative effect.