地塞米松治疗小儿大叶性肺炎的疗效分析

Curative effect of dexamethasone on treatment of children with lobar pneumonia

目的探讨地塞米松在大叶性肺炎治疗中应用的疗效。方法将80例大叶性肺炎患儿随机分成观察组40例和对照组40例,两组均给予抗炎、平喘、化痰等传统治疗,观察组给予地塞米松静脉注射,比较两组症状控制情况及住院时间。结果观察组总有效率95%(38/40)高于对照组72.5%(29/40),差异有统计学意义(Zc=5.219,P<0.05);两组治疗期间发热及咳嗽的减轻时间,呼吸困难缓解时间、肺部罗音消失时间、X片阴影消失时间以及住院时间比较,观察组均优于对照组,差异均有统计学意义(t值分别为6.906、4.858、5.960、3.094、2.619、2.428,均P<0.05)。结论在大叶性肺炎的治疗中合理应用地塞米松,能迅速控制病情,改善患儿的症状,缩短住院时间。

Objective To investigate the curative effect of dexamethasone on the treatment of lobar pneumonia. Methods Eighty cases of lobar pneumonia in children were randomly divided into observation group （40 cases） and control group （40 cases）. Two groups were given conventional treatment including anti-inflammatory, relieving asthma and resolving phlegm, and the observation group received intravenous injection of dexamethasone additionally. Symptoms control and hospitalization time were compared between two groups. Results The total effective rate of the observation group was 95% （38/40） , which was higher than that of the control group （72.5% , 29/40）, and the difference was statistically significant （Zc = 5. 219, P 〈 0.05 ）. During the treatment the observation group was superior to the control group in terms of time of fever and cough relief, time of dyspnea relief, time of lung rale disappearance, X-ray shadow disappearance time and length of hospital stay, and the differences were significant （t value was 6. 906, 4. 858, 5. 960, 3. 094, 2. 619 and 2. 428, respectively, all P 〈 0.05 ）. Conclusion In the treatment of lobar pneumonia in children, reasonable application of dexamethasone can control the illness, improve symptoms and shorten hospitalization length.