摘要
回顾性分析1987年至2014年6月在我院经临床和病理确诊的115例蕈样肉芽肿患者的临床资料。患者平均发病年龄39.03＆#177;18.10岁,平均确诊年龄43.99＆1±6.83岁,发病到确诊时间间隔4周~30年,平均4.92年。93.04％的患者皮损累及全身多个部位,非曝光部位更多见。组织病理显示87.83％出现亲表皮现象,78.26％出现淋巴细胞异型。免疫组化显示：肿瘤细胞绝大多数呈T辅助细胞标记,个别标记T细胞毒性细胞。35.65％的病例曾被误诊。早期干预性治疗多能使病情缓解或临床治愈。
The clinical data of 115 patients with mycosis fungoides from 1987 to 2014 were analyzed retro-spectively. The mean age of onset and diagnosis were 39.03＆#177;18.10 years and 43.99±16.83 years. The mean interval from onset to diagnosis was 4.92 years. The lesions were all over the whole body in 93.04% patients. Pathological characteristics included epidermotropism （ 87. 83%） and neoplastic T-lymphocytes （ 78. 26%） . Immunohistochemistry showed that the most of tumor cells were th cells and a few cells were cytotoxic T cell. 35.65% cases had been misdiagnosed. The treatment was effective for the early stage of MF.
出处
《中国麻风皮肤病杂志》
2015年第11期673-678,共6页
China Journal of Leprosy and Skin Diseases
