肠愈宁治疗溃疡性结肠炎(湿热蕴结兼脾虚型)临床观察

Clinical Observation of Chang Yu Ning Granules in the Treatment of Ulcerative Colitis(Damp-heat Stagnation and Spleen Deficiency Type)

目的:观察肠愈宁颗粒治疗溃疡性结肠炎临床疗效。方法:符合纳入标准的41例溃疡性结肠炎患者随机分为治疗组21例和对照组20例,治疗组采用自拟方剂肠愈宁颗粒联合艾迪莎进行治疗,对照组采用艾迪莎进行治疗,观察两组患者治疗前后炎症活动指数及肠镜下黏膜改变情况。结果:治疗组炎症活动指数反应疗效明显优于对照组(P<0.05);治疗组肠镜改变均优于对照组(P<0.05)。结论:肠愈宁颗粒治疗溃疡性结肠炎疗效明显。

Objective： To evaluate the efficacy of Chang Yu Ning granules on treating ulcerative colitis. Methods： 41 cases of ulcerative colitis were randomly divided into a treatment group with 21 cases and a control group with 20 cases. The treatment group received Chang Yu Ning granules combined with Etiasa and the control group only received Etiasa for the treatnent. The inflammatory activity index and endoscopic mucosa were observed before and after treatment. Results： In the treatment group the inflammatory activity index was significantly better than that in the control group（ P〈0. 05）; in the treatment group the colonoscopy change was superior to that in the control group（ P〈0. 05）. Conclusion： Chang Yu Ning granules could treat ulcerative colitis effectively.