静脉注射用人免疫球蛋白治疗小儿手足口病合并病毒性脑炎的合理性分析

Analysis of the rationality of human immunoglubin for intravenous injection in treatment of children with hand-foot-mouth diseases combined with viral encephalitis

目的:探讨静脉注射用人免疫球蛋白治疗手足口病合并病毒性脑炎的临床治疗意义。方法:选取2013年1月—2015年4月我院收治的手足口合并病毒性脑炎患儿184例,观察组117例,对照组67例。对照组使用常规治疗,观察组在常规治疗基础上加用静脉注射用人免疫球蛋白治疗。对比两组患者的临床治疗效果。结果:观察组患儿发热消退时间及神经系统症状消失时间>对照组、皮疹消退时间<对照组,但差异无统计学意义(P>0.05)。结论:手足口合并脑炎患者使用静脉注射用人免疫球蛋白不能缩短各临床症状改善时间。

Objective： To analyze the rationality of human immumoglobulin gamma globulin（IVIg） therapy in the treatment of viral encephalitis caused by hand-food-mouth disease （HFMD） in children.Methods： 184 patients with HFMD combined with viral encephalitis admitted to our hospital from January 2013 to April 2015 were divided into control group （67 cases） and treatment group （117 cases）. Both groups were given routine nursing and treatment. The treatment group was given human immumoglobulin gamma globulin. The clinical efifcacy in the two groups were observed.Results： After treatment, the fever process, rash disappearing time and time for nervous system pathological symptoms, all showed no statistically significantly differences （P〉0.05）.Conclusion：The treatment with human immumoglobulin gamma globulin may not improve the clinic efifcacy and shorten the duration of HFMD combined with viral encephalitis.