血管性血友病因子与偏头痛血瘀型相关性探讨

Study on Correlation Between Migrain with Stasis Syndrome and von Willebrand factor

目的:探讨血管性血友病因子与血瘀型偏头痛的相关性。方法:选择偏头痛发作期患者60例,分为血瘀型组(30例)和非血瘀型组(30例),同时选取健康对照组30例,检测血管性血友病因子(v WF)的含量,记录血瘀证积分、头痛指数。结果:各研究组间v WF含量水平有统计学意义,偏头痛组v WF、血瘀证积分、头痛指数3者之间均有直线相关性。结论:血管性血友病因子与偏头痛血瘀型关系密切,预测内皮细胞功能损伤可能参与偏头痛的发病机制,可为偏头痛血瘀证治疗采取活血化瘀、保护内皮功能的方法提供依据。

Objective： To investigate the yon Willebrand factor associated with Migrain with Stasis Syndrome.Methods： The selection of patients with migraine 60 patients, divided into blood stasis group （ 30 cases ） and non-blood stasis group （ 30 cases ）, and select the 30 cases as control group, detected the content of von Willebrand factor, record the stasis score and headache index. Resuhs ： the difference of three groups of von Willebrand factor （ vWF ） concentration levels were significant （ （ P〈0.01 ） ; VWF, blood stasis points, headache index among migraine group were linear correlation between them （P 〈0.01 ）.Conclusion： Concentration levels of yon Willebrand factor is closely related with the Stasis Syndrome of migraine, endothelial dysfunction can be predicted in the pathogenesis of migraine.and can be provided the basis for the treatment of migraine with the method of endothelial function protection and Huoxue Huayu.