塑料食包材料烷基酚聚氧乙烯醚迁移量的测定

Migration Determination of Alkyl Phenol Ethoxylates in Plastic Food Contact Materials

建立了高效液相色谱串联质谱法对塑料食品包装材料中烷基酚聚氧乙烯醚向食品模拟物迁移量的检测方法。使用5种食品模拟物：水、3%乙酸溶液（质量分数）、10%的乙醇溶液（体积分数）、95%的乙醇溶液（体积分数）和橄榄油。样品在40℃下浸泡240 h,以C18柱为分离柱,3%乙腈-77%甲醇-20%水为流动相分离,采用电喷雾串联四级杆进行检测。该方法对壬基酚聚氧乙烯醚的平均回收率为72.9%~104.6%,相对标准偏差为1.5%~11.2%,对辛基酚聚氧乙烯醚的平均回收率为94.9%~113.9%,相对标准偏差为2.6%~7.0%。

A new analytical method based on high performance liquid chromatography coupled with tandem mass spectrometry（HPLC-MS/MS） was developed for determining the migration of alkyl phenol ethoxylates from plastic food packaging materials into food simulants such as water, 3 % acetic acid solution（weight fraction）, 10 % ethanol solution（volume fraction）, 95 % ethanol solution（volume fraction）and olive oil. The contact with food simulants tests were carried out at 40 ℃ for 240 h. The anlalytes were separated on a C18 column using 3 % acetonitrile-77 % methanol-20 % water（volume fraction） as mobile phase, and then detected by HPLC-MS/MS using selective reaction monitoring（SRM） mode. The recoveries for nonylphenol polyethoxylates varied from 72.9 % to 104.6 % with the relative standard deviations ranging from 1.5 % to 11.2 %.The recoveries for octylphenol polyethoxylates varied from 94.9 % to 113.9 % with the relative standard deviations ranging from 2.6 % to 7.0 %.