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IVUS结合FFR指导冠脉临界病变介入治疗的价值 被引量：2

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摘要 目的分析冠脉内超声(intravascular ultrasound,IVUS)与血流储备分数(fractional flow reserve,FFR)检查在冠脉临界病变介入治疗中的应用价值。方法将63例冠状动脉造影为临界病变患者随机分为强化他汀药物治疗组、血运重建组和对照组,比较不良心血管事件的发生情况。结果血运重建组再发心绞痛1例;强化他汀药物治疗组中,出现急性心肌梗死1例,再发心绞痛2例;对照组中再发心绞痛2例。3组主要的不良心血管事件的发生率均较低。结论 FFR可作为冠状动脉临界病变是否需要经皮冠状动脉介入治疗(PCI)治疗的重要临床依据,FFR>0.75,IVUS检查能够提示不稳定斑块,单纯药物治疗是安全的。
作者 严新美 吴延庆 万红梅 徐劲松
机构地区 新余市人民医院 南昌大学第二附属医院
出处 《基层医学论坛》 2015年第31期4354-4355,共2页 The Medical Forum
关键词 冠心病 临界病变 血管内超声 血流储备 分数测定
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献4

  • 1Tobis J,Azarbal B, Slavin LAssessment of intermediate severitycoronary lesions in the catheterization laboratory [J].J Am Col] Cardiol, 2007,49 (8) : 839-848.
  • 2Kern M J, Samedy H.Current concepts of integrated coronary physiology in the catheterization laboratory [J].Joumal of the American College of Cardiology,2010,55( 3 ):173-185.
  • 3Pijls NHJ, de Bruyne B, Peels K, et al.Measurement of fractional flow reserve to assess the functional severity of coronary-artery stenoses [J]. New England Journal of Medicine, 1996,334 (26) : 1703-1708.
  • 4李勇,任法新,方毅民,杨军,刘少荣,王桂乐.临界血流储备分数指导中度冠状动脉病变治疗的临床价值[J].中华临床医师杂志（电子版）,2011,5(9):2704-2706. 被引量：9

二级参考文献13

  • 1Kern MJ,Lerman A,Bech JWet al.Physiological assessment of coronary artery disease in the cardiac catheterization laboratory:a scientific statement from the American Heart Association Committee on Diagnostic and Interventional Cardiac Catheterization,Council on Clinical Cardiology. Circulation . 2006
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  • 4Verna E,Lattanzio M,Ghiringhelli S,et al.Performing versus deferring coronary angioplasty based on functional evaluation of vessel stenosis by pressure measurements:a clinical outcome study. Cardiovascular Medicine . 2006
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  • 8Courtis J,Rodés Cabau J,Larose E,et al.Comparison of medicaltreatment and coronary revascularization in patients with moderatecoronary lesions and borderline fractional flow reserve measure-ments. Catheterization and Cardiovascular Interventions . 2008
  • 9Tani S,Watanabe 1,Kobari C,Matsumoto M,Miyazawa T,Iwamoto Y,et al.Mismatch between results of myocardial fractional flow reserve (FFR)measurements and myocardial perfusion SPECT for identification of the severity of ischemia:pitfall of FFR in patients with prior myocardial infarction. Japanese Heart Journal . 2004
  • 10Jeremias A,Whitboum RJ,Filardo SD,et al.Adequacy of intracoronary versus intravenous adenosine-induced maximal coronary hyperemia for fractional flow reserve. American Heart Journal . 2000

共引文献8

同被引文献15

引证文献2

二级引证文献11

基层医学论坛
2015年 第31期

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