艾地苯醌联合灯盏细辛治疗血管性痴呆的疗效及安全性分析

Efficacy and Safety of Idebenone Combined With Erigeron Breviscapus in Treatment of Vascular Dementia

目的探讨血管性痴呆应用艾地苯醌联合灯盏细辛治疗的疗效,以丰富临床治疗经验。方法选取2014年6月~2015年6月在我院收治的血管性痴呆患者86例,根据入院治疗顺序随机分成对照组与观察组各43例,对照组给予艾地苯醌治疗,观察组则使用艾地苯醌联合灯盏细辛予以治疗。经治疗后,统计两组的临床疗效,并进行对比。结果观察组的治疗总体有效率优于对照组,差异具有统计学意义（P〈0.05）;观察组的不良反应率则低于对照组,差异具有统计学意义（P〈0.05）。结论血管性痴呆应用艾地苯醌联合灯盏细辛提高治疗效果,且不良反应率低,安全可靠。

Objective To investigate the curative effect for treating the vascular dementia by the idebenone and erigeron breviscapus. By this way, to enrich the clinical treatment experience. Methods To select 86 cases of patients with the vascular dementia at our hospital from June,2014 to June,2015. They were randomly divided into the control group and the treatment group by the sequence of treatment,each group was 43 cases. The control group was treated by the idebenone. The treatment group was treat by the erigeron breviscapus. To compare the clinical effects of this two groups after treatment. Results The overall effective rate of the treatment group was significantly greater than the control group. Differences were statistically significant（P 0.05）. The adverse reaction rate of the treatment group was significantly less than the control group. Differences were statistically significant（P 0.05）. Conclusion The efficacy for treating the vascular dementia by the idebenone and erigeron breviscapus had low adverse reaction rate. That is safe and reliable.