双水平正压通气在新生儿呼吸窘迫综合征临床治疗中的应用

The Application of Double Horizontal Positive Pressure Ventilation in the Treatment of Neonatal Respiratory Distress Syndrome

目的探究新生儿呼吸窘迫综合征(NRDS)采用双水平正压通气(Duo-PAP)治疗方法的临床疗效。方法随机抽取我院64例NRDS患儿,并随机分为观察组和对照组。观察组采用Duo-PAP联合PS(肺表面活性物质)方法治疗。对照组采用鼻塞持续气道正压通气(NCPAP)与PS联合治疗的方法。比较两组患儿的临床指标变化。结果治疗后,两组患儿Pa O2水平与Pa CO2水平(P<0.05,P<0.01)均有所改善,在治疗3 h和12 h后效果尤为显著。在治疗成功率上,虽然观察组比对照组稍高,但差异无统计学意义。结论治疗NRDS采用Duo-PAP方法可提高治疗效率,使呼吸窘迫症状有效改善。

Objective To explore the clinical efficacy of double level positive pressure ventilation（Duo-PAP） in the treatment of neonatal respiratory distress syndrome（NRDS）. Methods 64 patients with NRDS were randomly divided into observation group and control group. The observation group was treated with Duo-PAP combined with PS（pulmonary surfactant therapy）. The control group was treated with nasal continuous positive airway pressure（NCPAP） and PS. The clinical indicators of the two groups were compared. Results After treatment, the levels of Pa O2 and Pa CO2 in the two groups were improved after treatment, and the effect of P and P was more significant in the treatment of 12 h and 3 h. On the success rate of treatment, although the observation group was slightly higher than the control group, but the difference was not significant. Conclusion Duo-PAP method can improve the efficiency of the treatment of NRDS, which can improve the symptoms of respiratory distress, and can be widely used in clinical treatment.