抗生素降阶梯治疗小儿重症肺炎的效果探析

Investigation on Treatment Effect of Antibiotic De-escalation for Children Patients with Severe Pneumonia

目的探析抗生素降阶梯治疗小儿重症肺炎的临床效果。方法搜集2014年9月~2015年9月在我院接受治疗的78例小儿重症肺炎患儿,随机分实验组和对照组。实验组39例患儿采用抗生素降阶梯治疗方法,对照组39例患儿采用常规治疗方法,观察并比较两组治疗效果。结果实验组患儿的治疗总有效率为97.44%,高于对照组患儿的治疗总有效率76.92%,实验组用药物时间与住院时间均短于对照组,两组相比差异,有统计学意义（P〈0.05）。结论抗生素降阶梯治疗方法可以有效治疗小儿重症肺炎,改善患儿的临床症状和缩短住院时间。

Objective Clinical effect of antibiotic de-escalation treatment for children patients with severe pneumonia is to be studied. Methods Choose 78 children patients with severe pneumonia who are treated in hospital from September 2014 to September 2015 and separate them into study group and control group at random, 39 patients in study group are given antibiotic de-escalation treatment, while 39 patients in control group are given conventional medication treatment, and then observe and compare treatment effects between two groups. Results Patients＇ treatment efficacy in study group is 97.44%, which is much higher than 76.92% in control group; besides, children patients＇ medication treatment course and their hospitalization days in study group are shorter than those of children patients in control group; there is a differential between two groups and such a differential has statistic value（P 0.05）. Conclusion Antibiotic de-escalation treatment is rather effective for children patients with severe pneumonia; it is conducive to relieving children patients＇ clinical symptoms and shortening their hospitalization days.