茶碱类药物在支气管哮喘治疗中的合理应用

Rational Use of Theophylline in the Treatment of Bronchial Asthma

目的研究分析支气管哮喘使用茶碱类药物治疗的临床效果。方法根据2012年3月~2014年3月我院的97例支气管哮喘患者,将这些患者分成对照组和实验组,对照组使用常规治疗,实验组使用常规治疗和茶碱类药物治疗,比较分析两组的临床治疗情况。结果实验组显效34例,好转11例,无效3例,总有效率为93.75%;对照组显效26例,好转10例,无效13例,总有效率为73.47%。实验组的临床治疗有效率比对照组高,两组结果差异具有统计学意义（P〈0.05）。结论茶碱类药物对支气管哮喘患者具有非常好的治疗效果,可以起到抗炎、调节免疫力、扩张支气管等作用,且副作用小。

Objective To study the clinical effect of the treatment of bronchial asthma with theophylline. Methods 97 cases of bronchial asthma patients were divided into control group and experimental group in our hospital from March 2012 to March 2014, the control group were treated with routine therapy, we used conventional treatment and the0phylline drugs, compared with two groups of clinical treatment. Results In the experimental group, 34 cases were markedly effective, 11 cases improved, 3 cases ineffective, the total effective rate was 93.75%, while the control group was 26 cases, 10 cases improved, 13 cases ineffective, the total effective rate was 73.47%. The clinical therapeutic efficacy of the experimental group was higher than that of the control group, and there was significant difference between the two groups （P〈0.05）. Conclusion Theophylline drugs have very good therapeutic effect in patients with bronchial asthma. It can play a role in anti inflammation, immune regulation, and expansion of the bronchus.