辛伐他汀治疗脑血栓的临床探析

Clinical Study on Simvastatin in Treatment of Cerebral Thrombosis

目的对辛伐他汀应用于脑血栓治疗中的临床效果进行分析探究。方法选取2013年11月~2015年3月在我院接受治疗的脑血栓患者71例,并随机分为阿司匹林组（34例）和辛伐他汀组（37例）,观察以上两种不同药物的治疗效果并比较。结果辛伐他汀组患者的基本痊愈率为54.1%,治疗总有效率为91.9%,均高于阿司匹林组的29.4%和70.6%;同时治疗6个月后,辛伐他汀组患者的颈动脉斑块IMT低于阿司匹林组,组间差异经t检验,具有统计学意义（P〈0.05）。结论辛伐他汀在脑血栓治疗中具有临床应用价值,具有延缓动脉粥样硬化的效果,对提高治疗效果以及降低死亡率具有显著的作用。

Objective Clinical effect of simvastatin in treatment of cerebral thrombosis is to be studied. Methods 71 patients of cerebral thrombosis who are treated in hospital from November 2013 to March 2015 were chosen and separate them into aspirin group （34 patients） and simvastatin group （37 patients） at random, and then observe and compare effects of these two medication treatments between two groups. Results Patients＇ cured rate in simvastatin group is 54.1% and its treatment efficacy is 91.9%, which are much higher than counterparts of 29.4% and 70.6% in aspirin group, besides, after 6 months of treatment, patients＇ IMT of carotid plaque in simvastatin group is lower than that in aspirin group, there is an efficacy differential between two groups according to t check and such a differential has statistic value （P〈0.05）. Conclusion Simvastatin is of efficacy in treatment of cerebral thrombosis, it is conducive to delaying atherosclerosis with efficaey and decreasing patients＇ mortality, thus, such a treatment is quite worthwhile to be promoted widespread.