奥美拉唑治疗胃溃疡合并出血的临床研究

Clinical Study on Omeprazole Treatment for Gastric Ulcer Complicated With Hemorrhage

目的对奥美拉唑应用于胃溃疡合并出血临床治疗中的效果进行分析研究。方法选取2013年11月~2015年9月在我院接受治疗的胃溃疡合并出血患者71例,并随机分为法莫替丁组（35例）和奥美拉唑组（36例）,观察比较两组的治疗效果。结果奥美拉唑组患者的显效率为72.2%,治疗总有效率为91.7%,均高于法莫替丁组的40%和74.3%;同时奥美拉唑组患者的平均止血时间短于法莫替丁组,HP转阴率高于法莫替丁组,组间差异经t检验,有统计学意义（P〈0.05）。结论奥美拉唑应用于胃溃疡合并出血临床治疗中的效果显著,能够促进患者快速止血,对提高HP转阴率以及促进患者康复具有重要作用。

Objective Clinical effect of omeprazole in treatment of gastric ulcer complicated with hemorrhage is to be studied. Methods 71 patients of gastric ulcer complicated with hemorrhage who are treated in hospital from November 2013 to September 2015 were chosen and separate them into famotidine group （35 patients） and omeprazole group （36 patients） at random, and then observe and compare treatment effects between two groups. Results Patients＇ explicit efficiency and treatment efficacy in omeprazole group are 72.2% and 91.7% respectively, which are much higher than counterparts of 40% and 74.3% in famotidine group, besides, patients＇ average hemostasis time is shorter and patients＇ negative rate of HP is quite higher in omeprazole group compared to counterparts in famotidine group, there is a differential between two groups according to t check and such a differential has statistic value （P〈0.05）. Conclusion Omeprazole is of efficacy in treatment of gastric ulcer complicated with hemorrhage, it is conducive to preventing from patients＇ hemorrhage, which is quite significant to increase their negative rate of HP and promote patients＇ health.