酮咯酸氨丁三醇在牙周治疗手术中的镇痛效果研究

Studay on the analgesic effects of ketorolac tromethamine for periodontal operation

将64例重度慢性牙周炎患者随机分为肌肉注射酮咯酸氨丁三醇组(KT组)和利多卡因局部神经阻滞麻醉组(L组)(n=32)在牙周手术治疗时采用VAS评估镇痛效果,并记录患者术中、术后的不良反应。术中2组VAS无统计学差异(P>0.05),术后6 h和12 h KT组VAS评分明显低于L组(P<0.05);术中L组全部出现口腔内局部轻度不良反应,KT组无任何局部不良反应出现(P<0.05);术后L组和KT组各观察到2例和1例轻度不良反应(P>0.05)。

64 patients with severe chronic periodontitis were divided into 2 groups（n = 32） randomly.Intramuscular injection of ketorolac tromethamine（KT group） and local block injection of lidocaine（L group） were respectively applied for periodontal subgingival scaling and root planning.The analgesic effect was assessed using VAS,the adverse drug reactions were recorded during and after operation.During operation the VAS between the 2 groups was not statistically different（P〉0.05）.6 and 12 h after operation the VAS of KT group was lower than that of L group（P〈0.05）.During operation minor intraoperative local adverse reactions were observed in all cases in L group,but not any in KT group（P〈0.05）;after operation minor adverse reactions were observed in 1 case of KT group and in 2 cases of L group（〉〈0.05）.