手足口病患儿心肌酶谱及血常规等各项指标的变化情况分析

Analysis of myocardial enzyme spectrum and blood routine and other index changes in children with hand foot and mouth disease

目的：探究手足口病患儿心肌酶谱各项指标的变化情况。方法：选取于2014年1月1日至2014年12月31日我院收治的50例手足口病患儿作为本次研究试验对象，取患儿及正常健康儿童静脉血液，检测心肌酶及血常规各项指标，分析比较。结果：观察组患儿血液中淋巴细胞、中性粒细胞以及红细胞含量均明显高于对照组正常儿童，但血红蛋白和红细胞压积低于同时期对照组健康儿童，两组比较有统计学意义（P〈0.05）。与正常健康组儿童相比，观察组患儿血清内CK、CK-MB、LDH、α-HBDH以及AST含量均明显上升，两组比较有统计学意义（P〈0.05）。经治疗后，观察组患儿CK、CK-MB、LDH、α-HBDH、AST等各项指标均有显著下降，与治疗前比较有统计学意义（P〈0.05）。结论：手足口病患儿发病时各项心肌酶谱指标均较正常健康儿童显著上升，经治疗后，明显下降，各项心肌酶谱指标和血液指标变化可能有利于手足口病的早期诊断，及早采取预防措施，预后较好，值得广泛推荐使用于临床当中。

Objective：To study the changes in child patients with HFMD myocardial enzyme indicators.Methods：50 cases of hand, foot and mouth disease in children as test subjects in this study from January 1, 2014 to December 31, 2014 in our hospital, taking HFMD children and healthy children venous blood, testing various myocardial enzymes and blood Routine indicators, analyzed and compared.Results：Group of children observed that blood cell nubmber of lymphocytes, neutrophils and erythrocytes were significantly higher than normal children, but hemoglobin and hematocrit were lower than the same period of the control group of healthy children, the two groups were statistically significant （P 〈0.05）. Compared with healthy group of children, in the observed group serum CK, CK-MB, LDH, α-HBDH and AST levels were significantly increased in both groups were statistically significant （P 〈0.05）. After treatment, patients in the observation group CK, the indicators CK-MB, LDH, α-HBDH, AST, etc. have decreased significantly compared with before treatment was statistically significant （P 〈0.05）.Conclusions：The incidence of hand, foot and mouth disease in children when the parameters were significantly increased myocardial enzymes healthy children, after treatment, significantly decreased the myocardial enzymes and blood indicators of change indicators may facilitate the early diagnosis of foot and mouth disease, early action preventive measures, the prognosis is good, it is widely recommended for use in clinical them.