小剂量右美托咪定对七氟烷吸入麻醉下行扁桃体摘除患者术后的影响

Effect of Small Dose of Dexmedetomidine on Sevoflurane Inhalation Anesthesia in Seven Patients after Tonsillectomy

目的:探究小剂量右美托咪定对七氟烷吸入麻醉下行扁桃体摘除患者术后躁动的影响。方法:选取125例七氟烷吸入麻醉下行扁桃体摘除术的患者,随机分成五组,各组于诱导开始后10min内,行右美托咪定[μg/(kg·h)]泵注,A组0.4,B组0.6,C组1.0μ,D组1.2,A^D组输至手术完毕束前15min;E组未予以右美托咪定泵注,对比五组临床效果。结果:(1)HR、Sp O2、SBP、DBP变化:A、B、C、E组T2、T3时HR、Sp O2均明显高于D组(P<0.05);(2)SAS及Ramsay镇静评分:B、C、D组均高于E组(P<0.05),SAS评分明显下降(P<0.05);(3)各项恢复时间:A、B、C唤醒时间、拔管时间及拔管后至送出麻醉恢复室时间均优于D组(P<0.05)。结论:对七氟烷吸入麻醉下行扁桃体摘除者推行0.6/(kg·h)右美托咪定泵注,可改善其术后躁动反应,安全可靠。

Objective： To explore small dose dexmedetomidine on sevoflurane inhalation anesthesia downward tonsil enucleation of agitation after effects. Methods： A total of 125 cases of sevoflurane inhaled anesthesia in tonsillectomy patients were randomly divided into five groups, groups in the minutes after the start of induction and medetomidine line set [μg/（kg·h）] infusion, a group of 0.4, group B, 0.6, group C 1.0 g, D group 1.2, a to D group to finish before the end of 15 min after the surgery; Group E fails to dexmedetomidine constant infusion, compared to five groups of clinical effect. Results：（1）The changes of HR, Sp O2, SBP, DBP： B, C, T2, E, T3, HR, A and Sp O2 were significantly higher than those in D group（P〈0.05）;（2） Ramsay and SAS sedation score： B, D, SAS were higher than E group（P〈0.05）;（3） the recovery time was better than D group（P〈0.05）.Conclusions： On sevoflurane inhalation anesthesia in tonsillectomy implementation 0.6μg/（kg·h） right dexmedetomidine midazolam infusion pump can improve the operation agitation after reaction, safe and reliable.