血清肿瘤标记物联合检测诊断胃癌的价值

Diagnosis of Gastric Cancer Combined Detection of Serum Tumor Markers

目的:研究血清肿瘤标记物在胃癌的联合诊断中的实际作用。方法:选取我院200例胃病患者,其中100例为胃癌患者,100例为胃良性病患者,利用电化学发光分析仪来对患者进行血清肿瘤标志物、糖类抗原的测定,分析单项肿瘤标志物与三项肿瘤标志物联合检测对于胃癌诊断的敏感性、特异性、阴性似然比等方面的影响。结果:观察组的三项血清肿瘤标记物检测数值明显高于对照组(P<0.05);胃癌患者通过血清肿瘤标记物联合检测诊断的敏感性、准确性上明显高于任一血清肿瘤标记物检测诊断(P<0.05)。结论:血清肿瘤标记物联合检测诊断对胃癌的诊断有着重要运用价值。

Objective： To study the practical effect of serum tumor markers in the diagnosis of gastric cancer. Methods：200 patients with gastric diseases, including 100 patients with gastric cancer, 100 patients with benign diseases, the use of electrochemical luminescence analyzer to determine the serum tumor markers, carbohydrate antigen, analysis of single tumor markers combined detection of three tumor markers for the diagnosis of gastric cancer, sensitivity, specificity, negative likelihood ratio, and so on. Results：The serum tumor markers in the observation group were significantly higher than those in the control group（P〈0.05）. The sensitivity and accuracy of the diagnosis of gastric cancer by serum tumor markers was significantly higher than that of any serum tumor markers（P〈0.05）. Conclusion：Combined detection of serum tumor markers in diagnosis of gastric cancer has important application value.