稳心颗粒联合酒石酸美托洛尔治疗冠心病室性心律失常患者的疗效观察

Observation of the Curative Effect of Wenxin Granule Combined with Metoprolol Tartrate in the Treatment of Coronary Heart Disease Ventricular Arrhythmia

目的探讨稳心颗粒联合酒石酸美托洛尔治疗冠心病室性心律失常患者的疗效。方法选取2012年10月至2014年10月在佛山市顺德区妇幼保健院就诊的98例冠心病室性心律失常患者作为研究对象,按随机数字表法将其分为对照组和观察组,各49例。对照组患者给予酒石酸美托洛尔,观察组患者在对照组基础上口服稳心颗粒,比较两组患者的临床疗效、QRS波时限和QTc间期、心律失常改善情况。结果观察组患者的总有效率明显高于对照组,差异有统计学意义(P<0.05);治疗后,观察组患者的QRS波时限明显短于对照组,QTc间期明显长于对照组,差异均有统计学意义(均P<0.05);治疗后,观察组患者的房室交界性期前收缩、房性期前收缩、室性期前收缩次数均明显低于对照组,差异均有统计学意义(均P<0.05)。结论稳心颗粒联合酒石酸美托洛尔治疗冠心病室性心律失常患者临床疗效明显。

Objective To investigate the clinical curative effect of Wenxin Granule Combined with metoprolol tartrate in treating coronary heart disease ventricular arrhythmia.Methods Select October 2012 to 2014 October in our hospital for treatment of 98 cases of crown ventricular cardiac arrhythmia patients as the research object,according to the random number table method wil be divided into the observation group and the control group,the 49 cases.The improvement of the control group were treated with metoprolol tartrate,groups of patients in the control group on the basis of oral Wenxin granule,compared two groups of patients with clinical observation,QRS duration and QTc interval, arrhythmia.Results The total effective rate of observation group was significantly higher than that of control group （P〈0.05）;the QRS wave duration was significantly shorter than that in control group（P〈0.05）,and the number of ventricular premature contraction,ventricular premature contraction,ventricular premature contraction in patients with atrioventricular junction was significantly lower than that in control group（P〈0.05）.Conclusion Wenxin Granule Combined with metoprolol tartrate in the treatment of the clinical curative effect of coronary heart disease ventricular arrhythmia significantly.