郑州地区无偿献血者的乙型肝炎表面抗原感染情况

Hepatitis B Surface Antigen Infection of Blood Donors in Zhengzhou Area

目的：探讨郑州地区无偿献血者乙型肝炎表面抗原（HBsAg）的感染情况。方法选取2014年1月至2014年6月郑州地区96820例无偿献血者作为研究对象，采用酶联免疫吸附试验（ELISA）检测HBsAg。结果18～25岁年龄组无偿献血者的HBsAg阳性率最高，其次为25～35岁年龄组；城市无偿献血者的HBsAg阳性率明显高于农村，差异有统计学意义（χ2＝6.337，P＜0.05）。结论低年龄城市无偿献血者的 HBsAg 阳性率较高，为了控制乙型肝炎病毒的传播，应提高国内ELISA试剂的灵敏度，加强对无偿献血者HBsAg阳性的筛查。

Objective To investigate the infection of hepatitis B surface antigen （HBsAg） in blood donors in Zhengzhou area.Methods From June 2014 to January 2014,96 820 cases of voluntary blood donors in Zhengzhou area were selected as the research object,using the enzyme linked immunosorbent assay （ELISA） to detect HBsAg. Results The positive rate of HBsAg was the highest in the 18 to 25 years old group,fol owed by 25 to 35 years old. The positive rate of HBsAg in the city was significantly higher than that in rural areas,the difference was statistical y significant（χ2=6.337,P〈0.05）.Conclution The positive rate of HBsAg of blood donors in low age cities is relatively high,in order to control the spread of hepatitis B virus,we should improve the sensitivity of the ELISA reagent,and strengthen the screening of HBsAg positive blood donors.