间断和持续蓝光照射治疗新生儿黄疸的临床效果比较

Comparison study on the clinical effect of intermittent and continuous blue light irradiation in the treatment of neonatal jaundice

目的:探讨对新生儿黄疸患者实施间断与持续性蓝光照射治疗的临床价值.方法:选取2013-10/2015-02我院收治的82例黄疸新生儿作为研究对象,并随机分组,对照组(n=41)选择持续性蓝光照射治疗,观察组(n=41)选择间断光照治疗,针对两组的具体光照情况作出比较和评估.结果:照射前,两组的血清胆红素值比较基本相当,差异无统计学意义(P>0.05);照射后,观察组的血清胆红素值相比对照组明显下降,差异具有统计学意义(P<0.05).在照射时间上,观察组为(4.13±1.25)d,与对照组的(6.32±1.81)d相比明显缩短,差异具有统计学意义(P<0.05).两组照射期间均有不适反应出现,且观察组不适反应的发生率为4.88%,低于对照组的19.51%,差异具有统计学意义(P<0.05).结论:采取间断光照治疗新生儿黄疸具有较好的效果,且安全可靠,利于缩短光照时间,适合临床推广.

AIM： To study the clinical value of intermittent and continuous blue light irradiation on neonatal jaundice. METHODS： A total of 82 cases of neonatal jaundice admitted into our hospital from October 2013 to February 2015 were randomly divided into control group（ n=41 ）and observation group（ n=41 ）. The control group was treated with continuous blue light irradiation, while the observation group was treated with intermittent light treatment, and specific lighting conditions between two groups were compared. RESULTS： The serum bilirubin level in the two groups were similar before the treatment, and no significant difference was observed（P〉0.05）. The serum bilirubin levels in the observation group was significantly decreased after the treatment compared with the control group, and the difference was statistically significant （P〈0.05）. The illumination time of observation group was （4.13± 1.25）d ,and that of control group was（6.32±1.81） d, which was longer than the observation group, the difference was statistically significant（P〈0.05）. During the irradiation, there was uncomfortable reactions between the two groups, and the uncomfortable reactions of observation group were observed for 4.88%, which was lower than the control group （19.51%）, the difference was statistically significant （P〈 0.05 ）. CONCLUSION ： It＇s safe and reliable to adopt intermittent lighting treatment for neonatal jaundice and it has a good effect. The method also can shorten the illumination time, which is suitable for clinical promotion.