急性胆源性胰腺炎的临床研究与分析

Clinical research and analysis of acute biliary pancreatitis

目的:探讨急性胆源性胰腺炎的临床治疗策略.方法:选取2014-01/2015-01我院收治的38例急性胆源性胰腺炎患者,根据病理检查、实验室检查结果分为梗阻组(n=16),行手术治疗;非梗阻组(n=22),行保守治疗和手术治疗.对比两组的临床疗效、术后并发症情况.结果:两组的治愈率、总有效率比较差异无统计学意义(P>0.05),而梗阻组的术后并发症率显著高于非梗阻组,差异具有统计学意义(P<0.05).结论:梗阻型急性胆源性胰腺炎患者病情急、危险大,应立即实施腹腔镜辅助下的胆囊切除术或取石并予以清创引流,而由于缺少抗炎治疗、胃肠减压、平衡电解质、抑酸等保守治疗措施,梗阻型急性胆源性胰腺炎患者在术后更容易发生并发症,在临床中对于急性胆源性胰腺炎患者宜采取病情评估、保守治疗和手术治疗相结合的策略.

AIM ： To investigate the clinical treatment strategy of acute biliary pancreatitis. METHODS： According to the results of pathological examination and laboratory examination, 38 patients admitted into our hospital from January 2014 to January 2015 with acute biliary pancreatitis were divided into obstruction group（n= 16） and non-obstruction group （ n = 22 ）. The former was treated by operation, and the latter were treated by non-operative treatment and operative treatment. The clinical efficacy and postoperative complications were compared between the two groups. RF.SULTS： The cure rate and total effective rate of the two groups were not statistically significant （P〉0.05）, and the postoperative complication rate in obstruction group was significantly higher than that of the non-obstruction group, the difference was statistically significant （P〈0.05）. CONCLUSION： The patients with obstructive ABP disease are urgent and dangerous, and they should be carried out laparoscopic cholecystectomy or stone removal and debridement and drainage, and due to the lack of anti-inflammatory treatment, gastrointestinal decompression, balanced electrolyte, acid suppression and other conservative treatment measures, patients with ABP are more prone to experiencing complications after surgery. Therefore, disease evaluation, conservative treatment and conservative treatment strategy should be applied to patients with ABP.