沙美特罗联合匹多莫德治疗COPD稳定期的疗效观察

Observation on the efficacy of salmeterol and pidotimod in the treatment of COPD

目的:观察并评价沙美特罗(SLT)+匹多莫德(PDT)治疗稳定期慢性阻塞性肺病(COPD)的临床效果.方法:选取我院在2013-04/2014-10确诊、收治的60例稳定期COPD患者作为研究对象,应用随机数表法将其分成观察组(n=30,采用SLT+PDT治疗方案)、对照组(n=30,接受单一PDT治疗),并比较两组的临床疗效、病情进展情况.结果:治疗后,观察组中显效、有效、无效分别为22例、6例和2例,本组显效率、总有效率分别为73.3%和93.3%,均显著高于对照组,差异具有统计学意义(P<0.05);自治疗开始至结束,观察组、对照组分别有0例、5例转为急重期,两组的急重期转入率相比较,差异具有统计学意义(P<0.05).结论:SLT+PDT治疗COPD的效果确切,值得临床应用.

AIM： To observe and evaluate the clinical effect of salmeterol （SLT） combined with pidotimod （PDT） in the treat- ment of stable stage of chronic obstructive lung disease （COPD）. METHODS ： A total of 60 cases of stable stage of COPD patients admitted into our hospital from April 2013 to October 2014 were selected as study objeclus and were randomly divided into observation group （n = 30, given the SLT＋PDT treatment） and control group （n = 30, given a single PDT treatment）. And the clinical curative effect and the progress of the disease of two groups were compared. RESULTS： After treatment, there were 22 cases with obvious effects （73.3%）, 6 cases only with effects and 2 cases without effects. The total effective rate was 93.3%, with significant differences （P〈0.05） ; A total of 5 cases in the control group developed into severe stage, and there was significant difference, when compared with observation group. CONCLUSION： The effect of combining SLT and PDT in the treatment of COPD was effective, and it is worthy of clinical application.