曲马多与舒芬太尼治疗瑞芬太尼复合麻醉术后急性疼痛的效果分析

Effect analysis of tramadol and sufentanil after remifentanil anesthesia in acute pain management

目的:观察并比较曲马多(tramadol,INN)和舒芬太尼(sufentanil,SFT)在瑞芬太尼麻醉后发生术后急痛治疗中的应用效果.方法:选择50例胸腹部外科手术者作为研究对象,并进行分组试验,分为观察组(n=25)和对照组(n=25).观察组患者予以SFT行术后镇痛治疗,对照组患者予以INN行术后镇痛治疗,观察比较两种方案的镇痛效果、不良反应情况.结果:与对照组相比,观察组患者在苏醒后10 min、30 min的疼痛评分更低、镇静评分值更高,差异具有统计学意义(P<0.05);另外,镇痛治疗期间观察组的不良反应率也明显低于对照组,差异有统计学意义(P<0.05).结论:SFT对于在瑞芬太尼复合麻醉下行外科手术的患者术后急痛的镇痛效果更佳、副作用更少,值得临床推广和应用.

AIM： To observe and compare the application effect of tramadol （ INN ） and sufentanil （ SFT ） after remifentanil anesthesia in acute pain management. METHODS： A total of 50 patients who underwent thoracic and abdominal surgery were selected as the research object and divided into observation group and control group by brigade laboratory method. The observation group and the control group were treated with SFT and INN for postoperative analgesia respectively. The analgesic effect and adverse reactions were observed and compared between two groups. RESULTS： Compared with the control group, the pain score of the observation group in 10 min and 30 rain after reviving was lower, while the sedation score values was higher. There were statistically significant differences between the two groups （P 〈 0.05）. In addition, during analgesic process, adverse reactions rate of the observation group was lower than that of the control group, with statistically significant difference （ P〈 0.05）. CONCLUSION： SFT has better analgesic effect and causes less side effect for the patients underwent remifentanil combined anesthesia. It is worthy of clinical promotion and application.