胰岛素泵治疗糖尿病的疗效探讨

Efficacy of Insulin Pump in the Treatment of Diabetes

目的探析胰岛素泵治疗糖尿病的临床疗效。方法整群选取该院2013年1月—2015年1月收治的65例糖尿病患者,在患者知情同意的情况下将其随机分为治疗组(32例)和对照组(33例),治疗组采取胰岛素泵治疗,对照组采取多次皮下注射,分析两组患者的治疗效果。结果治疗组总有效率为96.86%较对照组81.81%,比较差异有统计学意义(P<0.05);治疗组患者的餐前、餐后2 h、睡前、凌晨血糖分别为(5.6±1.5)mmol/L、(7.3±1.6)mmol/L、(5.8±1.4)mmol/L、(6.6±1.5)mmol/L与对照组的(8.1±2.4)mmol/L、(9.7±1.8)mmol/L、(8.4±1.6)mmol/L、(8.9±1.1)mmol/L比较,差异有统计学意义(P<0.05);治疗组发生低血糖的几率为(3/32)9.36%较对照组(10/33)30.30%比较,差异有统计学意义(χ2=12.481,P<0.05),两组均未发生意识丧失、大小便失禁等严重不良反应。结论应用胰岛素泵治疗糖尿病效果较好,安全有效,值得应用。

Objective To analyze the clinical effect of insulin pump in the treatment of diabetes. Methods 65 cases with diabetes admitted in the hospital from January 2013 to January 2015 were selected and randomly divided into the treatment group（32 cases）and the control group（33 cases） in the case of patients with informed consent. The treatment group was treated by insulin pump,and the control group was given subcutaneous injection of insulin. And the treatment effect of the two groups was analyzed. Results Compared with the control group, the treatment group had higher overall response rate（96.86% vs 81.81%） with statistically significant difference（P〈0.05）; The level of preprandial blood glucose, 2-hour postprandial blood glucose, bedtime blood glucose,early morning blood glucose was（5.6±1.5） mmol/L,（7.3±1.6） mmol/L,（5.8±1.4） mmol/L,（6.6±1.5） mmol/L, respectively, and（8.1±2.4） mmol/L,（9.7±1.8） mmol/L,（8.4±1.6） mmol/L,（8.9±1.1） mmol/L, respectively, the difference between the two groups was statistically significant（P〈0.05）. The incidence of hypoglycemia was 9.36%（3/32） in the treatment group, and 30.30%（10/33） in the control group, the difference was statistically significant（χ2=12.481,P〈0.05）. No unconsciousness and gatism and other severe adverse reactions occurred in both groups. Conclusion Insulin pump has better effect in the treatment of diabetes, it is safe and effective and worthy of application.