基底细胞癌的病理诊断分析及预后

Pathological Diagnosis and Prognostic of Basal Cell Carcinoma

目的探讨基底细胞癌的病理诊断分析及预后。方法整群选取2010年10月—2014年5月在该病理科进行基底细胞癌的病理诊断的74例患者作为研究对象,并对其病理资料进行回顾性分析。结果 74例基底细胞癌患者中,眶周部23例,占31.1%,峡部5例,占6.8%,额部9例,占12.2%,颧骨部7例,占9.4%,鼻翼部19例,占25.6%,上唇部6例,占8.1%,下颌部3例,占4.1%,背部2例,占2.7%。镜下可见瘤细胞团块状或巢状排列,细胞核大小不一,排列密集紊乱,胞浆少淡染,瘤细胞巢周围裂隙形成,间质慢性炎细胞浸润。结论基底细胞癌是皮肤科最常见的恶性肿瘤之一,及早进行病理诊断和治疗,预后较好,可以明显的提高患者的生命质量。

Objective To investigate the pathological diagnosis and the prognosis of basal cell carcinoma. Methods 74 patients who underwent pathological diagnosis of basal cell carcinoma in our hospital from October 2010 to May 2014 in the Department of Pathology of our hospital were selected as the research object and their pathological data were retrospectively analyzed. Results In all the 74 patients, basal cell carcinoma in periorbital region was found in 23 cases, accounting for 31.1%; in isthmus in 5 cases, accounting for 6.8%; in forehead in 9 cases, accounting for 12.2%, in the zygomatic in 7 cases, accounting for 9.4%, in alae nasi in 19 cases, accounting for 25.6%, in upper lip in 6 cases, accounting for 8.1%, in lower jaw in 3 cases, accounting for 4.1% and in back in 2 cases, accounted for 2.7%. Under the microscope, the tumor cells, of which the nucleus of difference size were ar-ranged dense and irregular, and of which the scanty cytoplasm was slightly stained, distributed in the form of round or spindle and of nest. Interstitial chronic inflammatory cell infiltration was developed in the fracture around tumor cells. Conclusion Basal cell carcinoma is one of the most common malignant tumors in the Department of Dermatology. Early pathological diagnosis and treat-ment can make the prognosis better and significantly improve the patient＇s quality of life.