介入合并清宫术在治疗剖宫产术后疤痕处妊娠的临床研究

Interventional Therapy Combined with Uterine Curettage in the Treatment of Cesarean Scar Pregnancy

目的探究剖宫产术后切口疤痕处妊娠不同治疗方法的疗效。方法回顾性分析该院2008年1月—2014年12月收治的剖宫产术后子宫疤痕处妊娠患者70例,根据具体情况,定治疗方式,分别行米非司酮+MTX治疗后行清宫术和行介入治疗后清宫术,即对照组和研究组,各35人。观察两组临床疗效。结果经过治疗,发现研究组的患者术中研究组β-HCG恢复至正常所用时间(21.3±2.5)d小于对照(47.3±6.1)d,而且研究组住院所用的时间(11.3±3.1)d也小于对照组的(17.6±3.5)d,两组比较差异有统计学意义(P<0.05)。结论介入治疗后清宫术在治疗剖宫产术后切口疤痕处妊娠的疗效明显优于米非司酮+MTX治疗后行清宫术,是目前值得推广应用的技术。

Objective To explore the curative effect of different treatment methods for cesarean scar pregnancy. Methods 70 pa-tients with cesarean scar pregnancy admitted to our hospital from January 2008 and December 2014 were treated with different methods according to concrete conditions.35 patients in the control group were treated with uterine curettage after MTX of mifepris-tone treatment, while the other 35 patients in the study group underwent interventional therapy combined with uterine curettage. The clinical curative effects of the two groups were observed. Results After treatment, β-hCG regression time, hospitalization time of the study group（21.3±2.5）d and （11.3±3.1）d respectively was less than that of the control group （47.3±6.1）d and （17.6±3.5）d respectively, and the differences were statistically significant （P〈0.05）. Conclusion The effect of interventional therapy combined with uterine curettage is superior to that of uterine curettage after MTX of mifepristone treatment, therefore it is worthy of popular-ization and application.