期刊文献+

广东佛山地区新发登革热流行的临床特征 被引量:7

Clinical characteristics of new cases with dengue fever in Foshan in Guangdong
原文传递
导出
摘要 目的总结2014年9—11月间佛山地区新发的106例登革热病人的临床特点。方法对2014年收治入院的新发106例登革热病人的临床症状、体征和实验室检查进行回顾性分析。结果 2014年的新发登革热病例主要临床表现为发热(100.0%)、头痛(82.1%)、关节肌肉痛(81.1%)、畏寒(70.8%)、咽充血(59.4%)、皮疹(38.7%)、淋巴结肿大(12.3%);实验室检查主要表现为AST升高(81.1%)、ALT升高(74.5%)、血小板减少(67.9%)、白细胞减少(60.4%)、低钾血症(24.5%)。结论此次佛山地区流行的新发登革热病例,临床表现典型,合并有多脏器损害,尤其肝损害较多见,部分病例出现低钾血症,未出现登革出血热(DHF)及登革休克综合征。经及时诊断和治疗,预后良好。 Objective To summarize the clinical characteristics of 106 new cases with dengue fever in Foshan areaduring September to November in 2014. Methods Of the clinical symptom,signs and laboratory examination results of the106 hospitalized patients were retrospectively analyzed. Results The clinical manifestation of the new cases with denguefever in 2014 were fever(100.0%),headache(82.1%),myalgia and ostealgia(81.1%),chilly(70.8%),pharyngal hyperaemia(59.4%),rash(38.7%),swelling of lymph node(12.3%); The major abnormal of laboratory examination were abnormal AST(81.1%),abnormal ALT(74.5%),thrombocytopenia(67.9%),leukopenia(60.4%),hypokalemia(24.5%). Conclusion The clinical manifestation of new cases with dengue fever in Foshan area was typical. Muitiple system organ injury,especiallythe liver function injury,was common. No dengue hemorrhagic fever or dengue shock syndrome was observed. The prognosiswas good because of timely diagnosis and treatment.
出处 《中国热带医学》 CAS 2015年第11期1396-1398,共3页 China Tropical Medicine
关键词 新发 登革热 临床特征 New cases Dengue fever Clinical characteristics
  • 相关文献

参考文献8

二级参考文献64

  • 1张复春,卢业成,陈燕清,王建,陈万山,尹炽标,杨湛,唐小平.2002至2003年广州及周边地区1032例登革热的临床特征[J].中华传染病杂志,2005,23(2):121-124. 被引量:36
  • 2[1]Kontny U,Kurane I, Ennis FA. Gamma interferon augments Fc gamma receptor-mediated dengue virus infection of human monocytic cells[J]. J Virol,1988;62:3928- 3933.
  • 3[2]Chen RF, Yeh WT, Yang MY, et al. A model of the real-time correlation of viral titers with immune reactions in antibody-dependent enhancement of dengue-2 infections[J]. FEMS Immunol Med Microbiol,2001; 30(1):1- 7.
  • 4[3]Green S, Pichyangkul S, Vaughn DW, et al. Early CD69 expression on peripheral blood lymphocytes from children with dengue hemorrhagic fever[J].J Infect Dis,1999;180(5):1429- 1435.
  • 5[4]King CA, Marshall JS, Alshurafa H, et al. Release of vasoactive cytokines by antibody-enhanced dengue virus infection of a human mast cell/basophil line[J]. J Virol,2000;74(15):7146- 7150.
  • 6[5]Huang YH, Lei HY, Liu HS, et al. Dengue virus infects human endothelial cells and induces IL-6 and IL-8 production[J]. Am J Trop Med Hyp,2000,63(1- 2):71- 75.
  • 7[6]King CA, Anderson R, Marshall JS. Dengue virus selectively induces human mast cell chemokine production[J].J Virol, 2002;76(16):8408- 8419.
  • 8[7]Elbishbishi EA, Agarwal R, Raghupathy R, et al. Sequential production of cytokines by dengue virus-infected human peripheral blood leukocyte cultures[J].J Med Virol,1999;59(3):335- 40.
  • 9[8]Chaturvedi UC, Elbishbishi EA, Agarwal R, et al. Cytotoxic factor-autoantibodies: possible role in the pathogenesis of dengue haemorrhagic fever[J]. FEMS Immunol Med Microbiol,2001;30(3):181- 186.
  • 10[9]Agarwal R, Chaturvedi UC, Misra A, et al. Production of cytotoxic factor by peripheral blood mononuclear cells (PBMC) in patients with dengue haemorrhagic fever[J]. Chin Exp Immunol,1998;112(3):477- 481.

共引文献68

同被引文献125

引证文献7

二级引证文献24

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部