大剂量氨溴索治疗ARDS的临床应用分析1例

The clinical application of large dose of Ambroxol Hydrochloride for the treatment of ARDS in 1 case

本文通过临床药师对一例使用大剂量氨溴索治疗ARDS的案例进行疗效、不良反应的追踪及分析,并查阅国内外相关文献,得出大剂量氨溴索治疗ARDS的应用证据不足,特别是对其疗效是否呈剂量相关性、给药剂量、给药频次还缺乏大规模的实验研究。因此,临床上应谨慎使用。

In this paper, the clinical pharmacist using large dose of ambroxol bydrocbloride in the treatment of acute respiratory distress syndrome （ARDS）for 1 case, curative effect and adverse reaction of were tracked and analyzed, and concluded that there is insufficient evidence for the application of large dose of ambroxol in the treatment of ARDS, especially no evidence for the effect-dose relationship, dose and dosing frequency from a large-scale experimental study. Therefore, it should be cautious in clinical use.