阻塞性睡眠呼吸暂停低通气综合征与血清晚期氧化蛋白产物的相关性

Analyze the relationships between gestational hypothyroidism and pregnancy outcomes

目的讨论血清晚期氧化蛋白产物AOPP与阻塞性睡眠呼吸暂停低通气综合征OSAHS的发生时的内在联系。方法将本院2014年10月至2015年6月这段期间内呼吸内科及重症监护室RICU内患有OSAHS（即阻塞性睡眠呼吸暂停低通气综合征）的患者100例作为实验组（轻度、中度、重度），对照组则为健康人群100名；测定上述的两组中的研究对象在该期间体内的AOPP血清氧化蛋白产物的水平，并分析两者之间的相关联系。所用方法为酶联法。结果AOPP的含量随该病病情严重程度的增加，含量也逐渐增高，结果对比很明显，具有统计学意义（P〈0．05）。实验组研究对象的AHI次数多于时照组的健康人群，夜间最低SaO2舍量也是低于健康人群的。是具有统计学意义的（P〈0．05）。结论血清晚期氧化蛋白产物（AOPP）对于OSAHS的监测具有十分重要的意义，两者具有正相关性。

Objective To improve pregnancy outcomes and protect the safety of the fetus,analyze and discuss the relationships between gestational hypothyroidism and pregnancy outcomes. Methods 100 patients with OSAHS from October 2014 June 2015 in Respiratory Medicine and ICU were chosen as the experimental group （mild,moderate, severe）, and 100 healthy people were chosen as the control group. AOPP serum levels of protein oxidation products of the two groups during the period were lested, and the links between them were analyzed. The method was ELISA. Results AOPP content increased with disease severity,which was sta tistically significant （P〈0.05）. AHI number of the experimental group was higher than the control group, Night minimum SaO2 content of the experimental group was lower than the control group,it was statistically significant （P〈0.05）. Conclusion AOPP has a great significance for OSAHS monitoring,and both have a positive correlation.