摘要
目的:探讨儿童EB病毒相关性嗜血细胞性淋巴组织增生症(EBV-HLH)的临床特征及其预后影响因素。方法随机选取2013年7月~2015年2月本院收治的EBV-HLH患儿66例,对其临床资料进行回顾性分析。结果66例患儿年龄以4个月~3岁为主,绝大部分均存在淋巴结、肝脾肿大现象,其中LDH>2000 U/L、SF>2000 ng/ml是影响EBV患儿预后的主要危险因素。结论低龄幼儿作为EBV的高发人群,可通过临床查体、血常规、EB-DNA定量检测等对其进行初步诊断,在治疗期间应加强对患儿生化指标的检测观察,以及时发现患儿的病情变化。
Objective The clinical features in children EB virus associated hemophagocytic lymphoproliferative disorder (EBV-HLH) and prognostic factors.Methods During July 2013 to February 2015 in our hospital the EBV-HLH children 66 cases were randomly selected , clinical data were retrospectively analyzed.Results 66 cases of children aged 4 months to 3 years old and most of them exist in the lymph nodes, liver and spleen enlargement phenomenon in which LDH〉 2 000 U/L, SF〉 2 000 ng/ml is a major risk factor for the prognosis of children with EBV.Conclusion EBV young children as high risk, through clinical examination, blood, EB-DNA quantitative detection of their initial diagnosis, during treatment observation of children should be strengthened to detect biochemical indicators, and found children's condition Variety.
出处
《中国继续医学教育》
2015年第30期87-88,共2页
China Continuing Medical Education
关键词
嗜血细胞性临床组织增生症
EB病毒
临床特征
预后分析
Bloodthirsty cell clinical tissue hyperplasia
EB virus
Clinical features
Prognosis analysis