醋酸泼尼松联合环磷酰胺治疗甲亢浸润性突眼的疗效观察

Efficacy of Prednisone Plus Cyclophosphamide in Treatment of Infiltrative Exophthalmos of Hyperthyroidism

目的探讨醋酸泼尼松联合环磷酰胺治疗甲亢浸润性突眼临床应用效果。方法对照组给予常规临床治疗,研究组在常规治疗基础上加用醋酸泼尼松联合环磷酰胺,记录两组甲亢浸润性突眼患者临床疗效。结果研究组甲亢浸润性突眼患者经治疗后获得高达90.00%的临床治疗总有效率,对照组仅获得75.00%的临床治疗总有效率(P<0.05)。结论经常规治疗联合醋酸泼尼松、环磷酰胺后甲亢浸润性突眼患者临床疗效获得显著提高,其生活质量得到有利保障。

Objective Discussion of prednisone and cyclophosphamide to treat hyperthyroidism exophthalmos invasive clinical effect.Methods The control group received routine clinical treatment, research group on the basis of conventional therapy plus prednisone plus cyclophosphamide, recording the clinical efficacy of the two groups of patients with hyperthyroidism infiltrative exophthalmos.Results Study group after infiltrating exophthalmos hyperthyroidism treated patients receive up to 90.00% of the total efifciency of the clinical treatment, the control group received only 75.00% of the total efficiency of the clinical treatment （P ＆lt;0.05）.Conclusion By conventional therapy combined with prednisone, clinical efifcacy in patients with hyperthyroidism inifltrative exophthalmos obtained after cyclophosphamide significantly improved, their quality of life has been a strong guarantee.