去氧孕烯炔雌醇与米非司酮治疗功能失调性子宫出血的疗效比较

Comparation on Desogestrel and Ethinyl Estradiol Mifepristone on Dysfunctional Uterine Bleeding

目的分析去氧孕烯炔雌醇与米非司酮治疗功能失调性子宫出血的临床疗效。方法将116例患者随机分为A、B两组各58例,A组给予去氧孕烯炔雌醇治疗,B组给予米非司酮治疗。结果 A组闭经率低于B组,复发率1.7%低于B组复发率8.6%,P<0.05;两组治疗后E2、P水平较治疗前降低,P<0.05;FSH、LH、T水平治疗前后无显著差异,P>0.05。结论去氧孕烯炔雌醇治疗功能失调性子宫出血效果显著。

Objective To analyze desogestrel ethinylestradiol and clinical effect of mifepristone treatment dysfunctional uterine bleeding. Methods 116 patients were randomly divided into A, B two groups, 58 cases in group A to give desogestrel ethinylestradiol treatment, B group was given mifepristone treatment.Results Amenorrhoea rate was lower than that in group B, group A recurrence rate 1.7% lower than that of group B 8.6% respectively,P〈0.05. The two groups after treatment, E2, P level was reduced,P〈0.05. There was no signiifcant difference between FSH, LH, T in two groups,P〉0.05.Conclusion Effect of Desogestrel ethinylestradiol in treatment of dysfunctional uterine bleeding is remarkable.