K-Ras基因突变在胰腺癌诊断、进展和预后中的作用研究进展

Research progress on K-Ras mutation used in pancreatic cancer patient's diagnosis, progression and prognosis

K-Ras基因突变是胰腺癌中最常见的基因改变类型之一,与胰腺癌的发生发展密切相关,并可能与胰腺癌的预后具有相关性。针对K-Ras基因突变在胰腺癌临床中作用的深入研究,将有助于胰腺癌的诊断与治疗。本文综述K-Ras基因突变在胰腺癌早期诊断、疾病进展及预后预测中的作用研究。

K-Ras gene mutation is a common genetic alteration in pancreatic cancer. Studies show that K-Ras gene mutation is closely related to the occurrence, progression and prognosis of pancreatic cancer. It may become an important target for future pancreatic cancer treatment. This review describes the recent progress of K-Ras mutation in diagnosis, progression and prognosis of pancreatic cancer.