高三酰甘油血症和动脉粥样硬化

Hypertriglyceridemia and atherosclerosis

低密度脂蛋白胆固醇增高是动脉粥样硬化和冠心病的重要危险因素,近年来大量研究结果表明高三酰甘油血症也是动脉粥样硬化和冠心病的重要危险因素。针对高三酰甘油血症的治疗可降低心血管事件的发生率。本文对三酰甘油的代谢、高三酰甘油血症和动脉粥样硬化的关系、高三酰甘油血症的治疗进展等作一简述。

It is well known that high plasma low density lipoprotein cholesterol is an important risk factor for atheroselerosis and coronary artery disease. Recently, a large amount of study showed that hypertriglyceri- demia was also the main risk factor for atherosclerosis and coronary artery disease. The treatment targeting hypertriglyceridemia may decrease the incidence of cardiovascular events. The metabolism of trigIyceride, the relation between bypertriglyceridemia and atherosclerosis, the advances of treatment for hypertriglyceridemia are reviewed in this paper.