针刺治疗手术后尿潴留临床疗效的Meta分析

Acupuncture for treatment of urinary retention postoperative: a systematic review and meta-analysis

目的系统评价针刺治疗手术后尿潴留的有效性和安全性。方法通过检索Pubmed、EMbase、中国期刊全文数据库(CNKI)、万方数据库、维普全文期刊数据库,纳入了针刺治疗手术后尿潴留的随机对照试验(randomized controlled trials,RCT)。采用考克蓝风险偏倚评估工具对纳入的研究进行质量评价。采用Cochrane协作网提供的Revman5.2软件对其进行Meta分析。结果最终纳入了符合标准的14篇文献,共1058例患者。本研究结果显示:合并OR值为3.49,95%可信区间CI(2.40,5.07),Z=6.54,P<0.00001,提示两组间差异有统计学意义,针刺治疗手术后尿潴留的有效率高于非针刺组。结论针刺疗法作为主要干预手段能够有效改善术后尿潴留的症状,针刺治疗本病较其他疗法有明显优势,但纳入研究的质量较低,样本量相对不足,仍需更多高质量的随机对照试验对其进行证实。

Objective To provide an reliable evidence for clinical practice, a systematic review and meta -analysis was performed to evaluate the efficacy and safety of acupuncture therapy for urinary retentionpostoperative. Methods Literature wasextraeted from Pubmed, EMbase, Chinese Journal Full -text Database （CNKI）, WanFang database, VIP full -text periodical database, we in- eluded the randomized controlled trials （randomized controlled trials, RCT） of acupuncture for treatment of urinary retention post- operative . ByCochrane collaboration＇s toll forassessing of bias to evaluate the quality of the included studies. The data were ana- lyzed by Revman 5.2 software provided by Cochrane network. Results A total of 14 papers（ 1058 patients） were includedin the Meta analysis. The results of the study showed that ： the merger effect quality odds ratios （OR） = 3.49, and 95 % confidence inter- val（CI） ：2.40,5.07 ,and the merger effect value test Z = 6.54 ,P 〈 0. 00001. Funnel chart shows that the results were roughly symmetry. Statistical difference indicates the therapeutic effect of acupuncture was better than the non - acupuncture. Conclusion The Meta analysis resuhs was a trend in favor of acupuncture effectiveness. However, due to low quality of included studies and there are no studies reporting adverse events ,further well- designed RCTs with high quality are still needed to evalu- ate the beneficial effects of acupotomoy.