冠心病冠状动脉病变严重程度与危险因素分析

Analysis of the Correlation Between the Severity of Coronary Artery Disease and the Risk Factors of the Disease

目的探究体检中心冠心病患者的冠状动脉的严重程度与冠心病的危险因素。方法整群选择2010年1月—2014年6月来该体检中心进行体检的280例冠心病患者,同时选取冠状动脉样硬化狭窄程度<50%的患者50例为对照组,对280例患者的冠状动脉的病变程度与患者的日常生活习惯及生理状况进行分析,采用Cemini积分来进行评定,分析与冠心病的危险因素存在的相关关系。结果患者的冠状动脉的病变程度与患者的年龄、是否有糖尿病、吸烟习惯、血脂异常及患者体质量指数的增长存在正相关的关系;冠心病组患者的男性、2型糖尿病、吸烟、高敏C-反应蛋白均高于对照组差异有统计学意义(P<0.05),而左心室射血分数、肌酐清除率水平、家族史构成比均低于对照组,差异有统计学意义(P<0.01)。结论冠心病患者多发于老年患者,若患者有吸烟习惯或伴随有糖尿病、血脂异常等相关疾病,可导致患者的冠状动脉病变更为严重,体检中心可指导该类患者的在康复治疗过程中养成良好的日常生活意识习惯,控制血糖、血脂水平,对于患者的治疗和预后有着重要的意义。

Objective To explore the correlation between the severity of coronary artery disease and the risk factors of the disease.Methods 280 cases with coronary heart disease underwent physical examination in the Medical Examination Center of our hospital from January 2010 to June 2014 were selected.And other 50 cases with coronary artery atherosclerosis stenosis 50%were selected as the control group.The severity of coronary heart disease and the daily habits and physical condition of the 280 cases with coronary heart disease were analyzed,and Cemini integral was used for assessing and analyzing the correlation between the severity of coronary heart disease and the risk factors of the disease.Results The severity of coronary artery disease had positive correlation with age,diabetes,smoking,dyslipidemia and the increase of body mass index.Compared with the control group,in the coronary artery disease group,there were more males,more type 2 diabetic patients,more patients with smoking habit,and the coronary artery disease group had higher level of sensitive C reactive protein（P〈0.05）.The coronary artery disease group had lower left ventricular ejection fraction and creatinine clearance rate and less proportion of patients with family history of coronary artery disease with statistically significant difference（P〈0.01）.Conclusion Coronary heart disease mainly occurs in elderly patients,and the disease will be more severe if the patients smoke or have diabetes,dyslipidemia and other relative diseases.The staff in the Medical Examination Center can guide the patients developing good daily habits and controlling the level of blood glucose and blood lipid,which is of great significance for the treatment and prognosis.