运动神经元病的临床及神经电生理分析

Diagnostic value of electroneurophysiological for Motor Neuron Disease

目的探讨神经电生理分析对运动神经元病(MND)诊断的临床价值。方法应用肌电图检测对23例MND患者神经电生理数据资料进行研究,并与对照组健康人40例进行比较分析。结果该院23例患者中,静息时出现纤颤电位19例(82.61%),正锐波17例(73.91%),肌肉轻收缩时运动电位的时限延长18例(78.26%),多相波波幅增高11例(47.83%),大力收缩时的电压增高22例(95.65%)。四肢肌肉的异常情况为71.33%,拇短展肌的异常情况为71.43%,胸锁乳突肌的异常情况为92.11%,MND组与对照组四肢MEP中枢运动传导时间,差异有统计学意义(P<0.05),MND组MEP值显著高于对照组。结论神经电生理技术的应用和推广,对诊断运动神经元病(MND)具有重要的临床价值,其中肌电图检测是诊断MND的重要手段。

Objective To investigate the Diagnostic value of electrophysiological for patients with motor neuron disease（MND.Methods The data of 23 patients with MND who had received electromyography test was studied and compared with that of the 40 healthy persons in the control group.Results 23 patients in hospital,resting fibrillation potentials was 19 cases（82.61%）,positive sharp wave was 17 cases（73.91%）,prolonged duration of motor unit potentials was 18 cases（78.26%）,multiphase wave amplitude increased was 11 cases（47.83%）,Voltage increased in strong contraction was 22 cases（95.65%）.The abnormal rate of limb muscles,abductor pollicis brevis,sternocleidomastoid uscle were separately 71.33%,71.43%and 92.11%.And nerve conduction：motor nerve conduc- tion velocity（MCV） and sensory nerve conduction velocity（SCV）,etc.Conclusion The application and promotion of neurophysiological techniques in the diagnosis of motor neuron disease（MND） has important clinical value,in which EMG detection is an important means..